Comparison of Inhibin A Immunoassays: Recommen- dation for Adoption of Standardized Reporting, Anand
نویسندگان
چکیده
dation for Adoption of Standardized Reporting, Anand S. Dighe, Frances J. Hayes, Javad Khosravi, Umesh Bodani, and Patrick M. Sluss ( Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114; 2 Diagnostic System Laboratories (Canada) Inc., Toronto, Ontario, Canada; 3 Diagnostics Systems Laboratories Inc., Webster, TX; 4 Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto and Mount Sinai Hospital, Toronto, Ontario, Canada; * author for correspondence: fax 617-726-9330, e-mail psluss@ partners.org)
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Granulosa Cell – Stromal Tumors: An Immunohistochemical Study Including Comparison of Calretinin and Inhibin
Background and Objective: Histopathological evaluation of granulosa cell tumors (GCT) of the ovary may be confused morphologically with a wide variety of the tumors. Immunohistochemical staining for inhibin and calretinin can be used for better diagnosis. Although it has been suggested that inhibin can be a sensitive marker for GCT, it maybe had negative results in some cases. In addition, cal...
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Background: Inhibin is a dimeric glycoprotein that has a depressive effect on the anterior hypophys secretion. The level of this tumor marker is undetectable in menopause women. In patients with gynecological cancer, especially granulosa and epidermal-type (mucinous), ovarian cancers considerable increase in the serum level of inhibin has been reported. The increased level of inhibin has been r...
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Exosomes are secreted by different types of cells and known as biological packages. Exosomes have significant role in intercellular communications and involved in the development and progression of various diseases such as cancer. Inhibin B and anti-mullerian hormone (AMH) are markers of granulosa cell tumors (GCT) and due to the role of exosomes in the progression of cancer, in this experiment...
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